Outlook 2010: Insert a smart card

We’re tracking a problem with Outlook 2010 clients in a domain environment receiving a pop-up dialog “Insert a smart card” when launching Outlook.  It also reoccurs while Outlook is open.  Mail flow is not affected.  Looks like it’s related to the recent Microsoft Update KB2553248 released yesterday, April 10, 2012.  Stay tuned.

Update: See Chris’ post here for the resolution.